Guillain-Barre Syndrome also known as GBS is an autoimmune disorder. It is an acute, rapidly progressive form of inflammatory polyneuropathy (inflammation of peripheral nerves) characterized by sensation impairment, muscle weakness usually affecting the lower limbs and gradually progressing up the limbs or complete paralysis, breathing difficulty. The syndrome can occur in men and women both and can occur at any age, but is most common between ages 30 and 50.

Causes: The exact cause of GBS is unknown, but some viral infection which may trigger GBS are Varicella-zoaster, Mumps and Cytomegalovirus. Also associated with Mycoplasam, Campylobacter, immunization with both live and dead vaccines, trauma, surgery, malignant disease and immunodeficiency.

Symptoms:

• Symmetrical weakness,
• Muscle weakness may be generalized or proximal distribution of the weakness or commences distally and ascends proximally,
• At the beginning sensory symptoms predominate with paresthesia of feet and then hands,
• Loss of deep tendon reflexes of arms and legs,
• Severe low back pain,
• Tenderness or muscle pain (cramp-like pain),
• Uncoordinated movements,
• Inability to walk,
• Autonomic dysfunctions,
• Palpitations,
• Blurred vision,
• Difficulty with eye movement, facial movement, speaking, chewing,
• Difficulty in breathing,
• Difficulty in swallowing,
• Low or high blood pressure.